Answer:
The correct answer is D. By treating a religious subject in a natural way.
Step-by-step explanation:
Giotto di Bondone, also known as Gioto was an Italian painter during the Late Middle Ages who lived in Florence, Italy. He is considered as one of the beginners of the Renaissance.
Giotto's art was important because he is considered to be the inflection point between the Byzantine art and the humanistic and realistic art. Due to this, the correct answer is letter D.