Plymouth people supported the Americans only. Jamestown had large plantations, while Plymouth consisted of small farms. ... Jamestown was established in 1607, while Plymouth was established in 1620. Jamestown had mostly men, while Plymouth consisted mostly of families.So, the difference between is that Roanoke was a failed colony, and Jamestown and Plymouth were successful. They were successful also because the Indians helped during their time of peace. This help gave the colonists time to succeed
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