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Answer:
37.5%
Explanation:
If the original price was $100 on Monday, then it was $80 on Tuesday. The Wednesday price of $50 is a $30 reduction from the Tuesday price, so represents a reduction of ...
$30/$80 × 100% = 37.5%
The store reduced its prices by 37.5% from Tuesday to Wednesday.
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Additional comment
20% of $100 is $20. A reduction of $20 from $100 gives a Tuesday price of $80.