Answer: If you take high doses of Adderall for a long time, your brain may become dependent on the drug and eventually produce less dopamine.
Explanation: Adderall as we know it today owes its origins to accident. In the late 1920s, an American chemist named Gordon Alles, searching for a treatment for asthma, synthesized a substance related to adrenaline, which was known to aid bronchial relaxation.