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All amino acid-based hormones are lipid soluble and can cross the plasma membrane.

True

False

User Ishpeck
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Amino acid derived hormones and polypeptide hormones are not lipid-derived (lipid-soluble) and therefore cannot diffuse through the plasma membrane of cells. Lipid insoluble hormones bind to receptors on the outer surface of the plasma membrane, via plasma membrane hormone receptors
User Elie Eid
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