Question

Which mechanisms is most significant in returning the ion concentrations to the resting state?

Answer 1

Active transport by the Na+-K+ pump

Step-by-step explanation:

Active transport by the Na+-K+ pump

Maintenance (and restoration) of the resting ion concentrations depends on the Na+-K+ pump. Once gated ion channels are closed, the combined action of the pump and ion leakage (particularly that of K+) establishes a resting membrane potential in a typical neuron of around âˆ'70 mV.