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How would an increased level of acetyl-CoA be expected to affect the pyruvate dehydrogenase reaction

User Toluju
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Answer:

The pyruvate dehydrogenase kinase enzyme activity would increase, resulting in an inhibition of pyruvate dehydrogenase activity. ... An in vitro study shows that isocitrate dehydrogenase is activated in the citrate cycle.

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User Chillyistkult
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