Question

Exercise 2: (7 points)

Augmentin
Augmentin is a drug formed by amoxicillin of molecular formula C16H19N3O5S.3H20 and molar mass 419 g.mol"! Augmenting is used to treat infections caused by certain bacteria. The normal dose is 500mg of tablet each 12 hours. The maximum dose is 40g of Augmentin for 10 days. Augmentin generally has a normal action; a high dose (overdose) in Augmentin causes kidney problems.
1) Explain in which case we use Augmentin. 2) 2.1) Il a patients dissolved in the water an Augmentin tablet of 500mg to prepare a 100ml solution, determine the mass concentration and molar concentration of the obtained solution 2.2) Write the procedures followed to prepare this solution and indicate the materials used in this preparation.
3) If a patient takes daily 100ml of Augmentin solution of concentration 50g L for 10 days, will he suffer from kidney problems?​

Answer 1

See explanation

Step-by-step explanation:

I) from the question;

500 × 10^-3 g dissolves in 100ml

xg dissolves in 1000ml

x = 500 × 10^-3 g × 1000ml/100 ml

x= 5 g/L

Mass concentration = molar concentration × molar mass

Molar concentration = Mass concentration/ molar mass

Molar concentration = 5g/L/419 g/mol

Molar concentration = 0.0119 M

ii) To prepare this solution, measure out 500mg with a weighing balance. Transfer the solid to a standard 100 ml volumetric flask. Make up to the 100ml mark with distilled water.

iii) mass concentration of the solution = 50 g/L

Volume of the solution= 100 ml

Mass of the solid = 50 g/L × 100/1000 L

Mass of solid = 5g

This 5g was taken for 10 days, hence a total of 50 g

Since the normal dose of the drug is 40g for ten days, the patient will suffer from kidney problems because he/she has taken the drug above the recommended dosage.