195k views
5 votes
Which best describes the different mechanisms of mitoxantrone and carboplatin

User Tkerwood
by
3.2k points

1 Answer

2 votes

Answer:

Step-by-step explanation:

Carboplatin undergoes activation inside cells and forms reactive platinum complexes that cause the intra- and inter-strand cross-linkage of DNA molecules within the cell. This modifies the DNA structure and inhibits DNA synthesis. This may affect a cell in all the phases of its cycle.

User Hectooorr
by
3.2k points