Question

Click and drag the terms on the left to accurately complete the sentences on the right. Then, arrange the sentences from top to bottom in order of least common to most common.

T cells, B cells, lymph node, destroyed, macrophage, immune response, antigen presenting cell, bound to transport proteins
a) Infected or malignant cells are then _______ before they can do further harm to the body.
b) The antigen presenting cell displays the antigen to the _______.
c) The T cells initiate the ________ if the antigens are viral proteins or abnormal antigens.
d) The _________ encounters and processes the antigen.
e) With the antigen, the antigen presenting cell migrates to the nearest ____________.

Answer 1

The immune response sequence starts with a macrophage encountering an antigen, followed by antigen presentation to T cells at a lymph node, T cell activation, and ultimately the destruction of harmful cells.

Step-by-step explanation:

The process of antigen presentation and subsequent immune response is critical for the body to combat infections. Here is the correctly completed sequence based on the antigen presentation and activation of T cells:

The macrophage encounters and processes the antigen.

With the antigen, the antigen presenting cell migrates to the nearest lymph node.

The antigen presenting cell displays the antigen to the T cells.

The T cells initiate the immune response if the antigens are viral proteins or abnormal antigens.

Infected or malignant cells are then destroyed before they can do further harm to the body.

This sequence ranges from the initial encounter with the antigen to the elimination of harmful cells, highlighting the progressive stages of the immune response.

Answer 2

d) The antigen-presenting cell encounters and processes the antigen.

e) With the antigen, the antigen-presenting cell migrates to the nearest lymph node.

b) The antigen-presenting cell displays the antigen to the T cells.

c) The T cells initiate the immune response if the antigens are viral proteins or abnormal antigens.

a) Infected or malignant cells are then destroyed before they can do further harm to the body.

Step-by-step explanation:

The antigen-presenting cells (e.g., dendritic cells, macrophages) are cells of the immune system that mediate cellular immune responses by processing and presenting antigens (i.e., peptides components of pathogens) to T lymphocytes. The antigen-presenting cells travel through lymphatic vessels from the site of infection to the lymph nodes where they present antigens to naive T cells, i.e., T cells that have matured but have not yet encountered their corresponding antigens. This presentation facilitates the clonal expansion of T cells that are specific for the antigen which acquire effector functions in order to destroy infected cells. This process is known as immune clearance and is associated with the apoptosis of antigen-specific T cells.