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Why is tetra methyl silane (CH3)4Si is used as a reference sample in NMR spectrometry?? I mean what are the properties of TMS that make it suitable for being used as a reference sample??

User IDroid
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TMS has 12 protons which are all equivalent and four carbons, which are also all equivalent. This means that it gives a single, strong signal in the spectrum, which turns out to be outside the range of most other signals, especially from organic compounds.

User Eana Hufwe
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