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How a mutation in DNA can lead to the symptoms of piebaldism?

1 Answer

12 votes

Answer:

skin that lack pigmentation.

Step-by-step explanation:

The KIT gene mutations responsible for piebaldism lead to a nonfunctional KIT protein. The loss of KIT signaling is thought to disrupt the growth and division (proliferation) and movement (migration) of melanocytes during development, resulting in patches of skin that lack pigmentation.

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