Question

Explain why the ability of PLP to catalyze an amino acid transformation is greatly reduced if the OHOH substituent of pyridoxal phosphate is replaced by OCH3OCH3.

Answer 1

Following are the responses to the given question:

Step-by-step explanation:

In the given question the OH could be generated as the H-bond with both the N (nitrogen), which is used to place its N as the partially positive value(+). It is used to simplifies the addition for either its AA with the imine C. In the above H-bond, the w N is not required as the possibility to use the OCH3