Final answer:
Prokaryotic cells lack a nucleus and other membrane-bound organelles, while eukaryotic cells have a true nucleus enclosed within a nuclear membrane and various membrane-bound organelles.
Step-by-step explanation:
Prokaryotic cells lack a nucleus and other membrane-bound organelles, such as mitochondria, chloroplasts, endoplasmic reticulum, and vesicles. They also lack a membrane-bound nucleus, and their genetic material is located in a region called the nucleoid. In contrast, eukaryotic cells have a true nucleus enclosed within a nuclear membrane and various membrane-bound organelles.