Step-by-step explanation:
Centrosomes is a clear space of cytoplasm located close to the nucleus. Whereas the chromosome is a highly coiled stricture contained in the nucleus.
Centrosome has usually one present per cell. Chromosomes can have one or more.
Centrosome consists of two rod-like strictures made of the protein tubulin. Chromosomes consist of DNA coiled around the histone protein core.