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What Native American groups stood in the way of this expansion?

User Olathe
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Answer:

This area was home to the Cherokee, Creek, Choctaw, Chicasaw, and Seminole nations. These Indian nations, in the view of the settlers and many other white Americans, were standing in the way of progress. Eager for land to raise cotton, the settlers pressured the federal government to acquire Indian territory.

Combatants: Seminole

Step-by-step explanation:

User Shoter
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