Answer: The part of the enzyme where the substrate binds is called the active site (since that's where the catalytic “action” happens). ... Thanks to these amino acids, an enzyme's active site is uniquely suited to bind to a particular target—the enzyme's substrate or substrates—and help them undergo a chemical reaction. To catalyze a reaction, an enzyme will grab on (bind) to one or more reactant molecules. These molecules are the enzyme's substrates. In some reactions, one substrate is broken down into multiple products. ... The products then leave the active site of the enzyme.
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