Question

Which sentence uses commas correctly? O How often, should she take this medicine Doctor? Run Isaac, run! O Come on, Scott, unlock this door! O Alec where are, your soccer cleats?​

Answer 1

I'm assuming your answer is:

Come on, Scott, unlock this door!

Step-by-step explanation:

How often, should she take this medicine Doctor?

There should be a comma in front of Doctor, after medicine. The sentence should not have a comma after often and before should.

(How often should she take this medicine, Doctor?)

Alec where are, your soccer cleats?​

The comma should be right after Alec's name, before the word where.

(Alec, where are your soccer cleats?)

Run Isaac, run!

I think that you need a comma after run, and before Isaac.

(Run, Isaac, run!)