Question

You are working with an acute slice of mammalian hippocampus in a bath of artificial cerebrospinal fluid In your first experiment, you stimulate the mossy fiber projection with an extremely strong stimulus while patch clamp recording from the postsynaptic neuron. When the presynaptic axons are electrically stimulated, which of the following sequence of events occurs?

a. Opening of voltage gated calcium channels in CA1 neuron dendrites, release of glutamate containing vesicles into the synapse, potassium influx in CA3 neuron
b. Opening of voltage gated sodium channels in dentate gyrus axons, fusion of GABA containing vesicles with the presynaptic membrane, opening of GABA-gated ion channels, chloride influx into CA3 neurons
c. Opening of voltage gated calcium channels in CA3 neuron axons, fusion of glutamate containing vesicles to the presynaptic membrane, opening of voltage gated sodium channels in CA1 neuron dendrites, sodium influx into CA1 neurons
d. Opening of voltage gated calcium channels in dentate gyrus axons, fusion of glutamate containing vesicles to the presynaptic membrane, opening of AMPA receptors in CA3 neuron dendrites, sodium influx into CA3 neurons

Answer 1

d. Opening of voltage gated calcium channels in dentate gyrus axons, fusion of glutamate containing vesicles to the presynaptic membrane, opening of AMPA receptors in CA3 neuron dendrites, sodium influx into CA3 neurons.

Step-by-step explanation:

From the little information given above in the excerpts, it could be seen that, the sequence of events that would occur when the mossy fiber is stimulated with an extremely strong stimulus is what was given above.