Answer:
The immune system is a host defence system that combines multiple mechanisms to protect an organism from several pathogens and the development of disease. The endocrine and immune system crosstalk and multiple immune processes are involved in endocrine diseases. Defects of immune tolerance associated with genetic and environmental factors result to the development of autoimmune diseases such as autoimmune thyroiditis and diabetes mellitus type 1. In addition, a mixture of immune cells and mediators is considered to be implicated in thyroid cancer development and progression. Multiple cytokines and the evolving inflammatory process are involved in the pathogenesis of insulin resistance and diabetes mellitus type 2 whereas immune mechanisms related to lymphocytes and cytokine circuits may play a role in the pathogenesis of osteoporosis. Several studies have recently been published regarding the therapeutic implications of immune system mechanisms on endocrine diseases. For complete coverage of all related areas