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Transmission across a synapse is achieved mainly by:

ionic bonding
diffusion of a neurotransmitter across the cleft
physical contact of axon to dendrite
diffusion of sodium ions across the cleft

User Beefcake
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Answer:

diffusion of a neurotransmitter across the cleft

Step-by-step explanation:

Transmission across a synapse is achieved mainly by: diffusion of neurotransmitter across the cleft.

User Lcs
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