Anticholinergic agent.
Anticholinergic agents are considered first-line
medications for urge incontinence. Estrogen
decreases obstruction to urine flow by restoring
the mucosal, vascular, and muscular integrity of
the urethra. Tricyclic antidepressants decrease
bladder contractions as well as increase bladder
neck resistance. Stress incontinence may be
treated using pseudoephedrine and
phenylpropanolamine, ingredients found in over-
the-counter decongestants.