The most important factor that enabled the Spanish to conquer native peoples in Mexico and New Spain in the sixteenth century was the
introduction of cattle and pigs, which disrupted native patterns of agriculture
introduction of European diseases to which native peoples were not resistant
introduction of Christianity, which weakened the solidarity of native peoples
superior horsemanship displayed by the Spanish conquistadores
Answer:
introduction of European diseases to which native peoples were not resistant
Step-by-step explanation:
The introduction of European diseases which the natives had no immunity to was one major factor that helped them to conquer native peoples in Mexico and New Spain in the sixteenth century