Answer: True
Step-by-step explanation:
Multiple issues between the Northern and Southern states led to the outbreak of the Civil War but the chief reason was slavery. The Southern states wanted to preserve it and the Northern states were increasingly making it difficult for the south to do so.
The Southern states responded by seceding from the Union and due to some skirmishes afterwards, war broke out as the Union tried to bring the Southern states back into the Union and end slavery as well.