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How did a belief in manifest destiny both lead the United States into a war with Mexico and fuel
a divisive debate over the extension of slavery?

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Answer:

The philosophy drove 19th-century U.S. territorial expansion and was used to justify the forced removal of Native Americans and other groups from their homes. The rapid expansion of the United States intensified the issue of slavery as new states were added to the Union, leading to the outbreak of the Civil War.

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