Question

Descriptions of enzyme mechanisms often contain the terms intermediate, transition state, and transition state analogue. The terms intermediate and transition state both describe chemical species along the reaction pathway, but there are important distinctions between the two. Transition state analogues are often used in enzyme mechanism studies. Match each phrase to the term that it describes.

a. Compound designed to mimic the structure of a transition state
b. Contains partially formed and partially broken bonds
d. Often serves as a potent enzyme inhibior

Answer 1

The intermediate state and the transition state are used to describe the chemical species that is along the reaction pathway.

Therefore, the phrase of the term that it describes each of the terms, intermediate, transition state analogue and transition state are as follows :

a. Compound which is designed to mimic the structure of the transition state

-- transition state analogue

b. Containing partially formed as well as partially broken bonds.

-- transition state

d. Often serves as the potent enzyme inhibitor

-- transition state analogue