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10. A woman who has hemophilia marries a normal man. How many of their children will have

hemophilia, and what is their sex?

1 Answer

3 votes

Answer:

The correct answer is - 50% of children will have hemophilia and all will be male.

Step-by-step explanation:

Hemophilia is a sex-linked recessive genetic disorder that occurs mostly in males due to the fact that to express this disease both the dominant copy of the gene should be absent. In males, there is only one X chromosome so the chances of being masked by the dominant allele are zero. While In women there are two X chromosomes so to express this disease both alleles need to be recessive.

Thus,

Hemophilic women marry (XhXh) with a normal man (XY)

Gametes will be - Xh, Xh and X, Y

Xh Xh

X XXh XXh

Y XhY XhY

Xh is here allele for hemophilic and X is normal, then there are 2 carrier women and two disease males will be produced.

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