Final answer:
The wood frog's cellular glucose concentrations increase to prevent ice formation by lowering the freezing point of the intracellular fluid, effectively inhibiting the growth of ice crystals within the cells.
Step-by-step explanation:
When the wood frog's liver produces large amounts of glucose in response to extremely cold conditions, the glucose accumulates in the frog's cells. This adaptation helps prevent ice from forming inside the cells by lowering the freezing point of the intracellular fluid. The glucose molecules interfere with the formation of the ice lattice because they cannot be incorporated into the lattice structure, hence decreasing the rate of freezing.
As a result, the temperature needs to be lowered further for the dynamic equilibrium between solid and liquid water to reestablish, meaning that freezing within the frog's cells is less likely to occur at the same temperatures that would normally cause water to freeze.