Question

Python-What is the fix? I’m do desperate.

Answer 1

numbers.append(z)

should have round parenthesis and should (probably) be indented like the z=... line.

Step-by-step explanation:

It is unclear what you expect the program to do.

In the last line you probably don't want the and-operator, but something like this:

print("{} and {}".format(numbers[0], numbers[4]))