191k views
21 votes
Brefly explain Endogenous antigen & examples & autoantigen​

User Ren P
by
4.7k points

1 Answer

8 votes

Exogenous antigens refer to the antigens that enter the body of the organism from the outside while endogenous antigens refer to the antigens produced from within the cell as a part of normal cell metabolism or when the cell is infected by bacteria or viruses.

Examples

viral proteins produced during viral replication;

proteins produced by intracellular bacteria such as Rickettsias and Chlamydias during their replication;

proteins that have escaped into the cytosol from the phagosome of phagocytes such as antigen-presenting cells;

User Joehl
by
5.7k points