Granulomatous inflammation is a type of immune response that occurs when the body is trying to eliminate a foreign substance or tissue. It is characterized by the formation of granulomas, which are clusters of immune cells that surround and isolate the substance or tissue in order to prevent its spread. Granulomas can occur in any part of the body and can be caused by a variety of different stimuli, including infections, allergies, autoimmune diseases, and other forms of injury or damage.
Three examples of granulomatous inflammation include:
- Tuberculosis: Tuberculosis is an infectious disease caused by the bacterium Mycobacterium tuberculosis. It often causes granulomatous inflammation in the lungs, but it can also affect other organs and tissues.
- Sarcoidosis: Sarcoidosis is a chronic autoimmune disorder that causes granulomas to form in various organs and tissues. It is often difficult to diagnose, as it can present with a wide range of symptoms, including lung problems, skin rashes, eye inflammation, and fatigue.
- Crohn's disease: Crohn's disease is a chronic inflammatory disorder that affects the digestive system. It is characterized by the formation of granulomas in the intestinal wall, which can lead to abdominal pain, diarrhea, weight loss, and other symptoms.