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In both eukaryotes and prokaryotes, gene expression is primarily regulated at the level of

User Jon Susiak
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Gene expression in prokaryotes is mostly regulated at the transcriptional level (some epigenetic and post-translational regulation is also present), whereas in eukaryotic cells, gene expression is regulated at the epigenetic, transcriptional, post-transcriptional, translational, and post-translational levels.

User Arta
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