Answer: The way that these issues influenced exploration and colonization in North America was that their exploration was fueled by the desire to obtain more wealth, ,more power(politics), and to spread their religion. European nations established colonies in North America for this reasons. European colonization of North America had a devastating effect on the native population. Within a short period of time their way of life was changed forever. The changes were caused by a number of factors, including loss of land, disease, enforced laws which violated their culture and much more.
Explanation: I hope that sums it up mostly.