Final answer:
Pancreatic juice production is stimulated by secretin and cholecystokinin (CCK), both of which respond to the presence of acidic chyme, proteins, and fats in the duodenum, and by parasympathetic impulses during the cephalic and gastric phases of gastric secretion.
Step-by-step explanation:
The factors that stimulate the production of pancreatic juice include the following hormones and nervous system impulses:
- Secretin: This hormone is released when acidic chyme enters the duodenum, stimulating the pancreas to release bicarbonate-rich pancreatic juice.
- Cholecystokinin (CCK): The presence of proteins and fats in the duodenum triggers the secretion of CCK, which in turn stimulates the enzyme-rich pancreatic juice secretion and enhances the activity of secretin.
- Parasympathetic impulses: These occur mainly during the cephalic and gastric phases of gastric secretion, when vagal stimulation prompts the secretion of pancreatic juice.
While gastrin does play a role in the gastrointestinal system by stimulating the secretion of gastric acid, it is not primarily responsible for the stimulation of pancreatic juice production.