Question

Compared with shotgun sequencing of double‑stranded dna, would genome assembly be easier or harder on this other planet where dna is single‑stranded? why?.

Answer 1

Genome assembly would be harder on the other planet where DNA is single-stranded due to the lack of a complementary strand for sequencing overlaps.

Step-by-step explanation:

In terms of genome assembly, it would be harder on the other planet where DNA is single-stranded.

Shotgun sequencing, which is commonly used for double-stranded DNA, relies on the ability to sequence overlapping fragments to reconstruct the entire DNA sequence.

However, with single-stranded DNA, the lack of a complementary strand makes it more challenging to determine overlaps accurately and assemble the genome.

Without the pairing information from the complementary strand, the process becomes more complex.