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What happened in 1901 that dramatically affected U.S. politics

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Answer:

September 6 – William McKinley assassination: American anarchist Leon Czolgosz shoots U.S. President William McKinley at the Pan-American Exposition in Buffalo, New York. McKinley dies 8 days later. September 7 – The Boxer Rebellion in China officially ends, with the signing of the Boxer Protocol.

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