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Given the following gene sequence, determine which of the choices would be a frameshift mutation:ATCTAGGTACTAA. ATTAGGTACTAB. ATTTAGGTACTAC. ATCATGGATCTAD. GTCTGGGTGCTG

User Kira Hao
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1 Answer

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To answer this question we need to remember what a frameshift mutation is: a mutation that implies an insertion or deletion of a nucleotide changing the letters that integrate each codon.

Original sequence: ATCTAGGTACTA

Comparison option by option

A T C T A G G T A C T A option A

A T - T A G G T A C T A

A T C T A G G T A C T A option B

A T T T A G G T A C T A

A T C T A G G T A C T A option C

A T C A T G G A T C T A

A T C T A G G T A C T A option D

G T C T G G G T G C T G

As we can see, options B and C are equal, option D has mutation but not insertion o deletion so does not apply, therefore we have left A, where we can see a deletion at the third base, Therefore the correct answer is option A.

User MG Lolenstine
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