In order to find the quadrants of y = -2/x, let's choose a positive and a negative value of x, then we calculate the corresponding values of y and check the quadrants:
![\begin{gathered} x=-2\colon \\ y=-(2)/(-2)=1 \\ \\ x=2\colon \\ y=-(2)/(2)=-1 \end{gathered}](https://img.qammunity.org/2023/formulas/mathematics/college/bavrsry49liosa7xilgpvfg591v79o0uur.png)
The point (-2, 1) is in quadrant II (negative x and positive y) and the point (2, -1) is in quadrant IV (positive x and negative y).
Therefore the correct option is C.