Answer:
A. The gene coding for the antigen can be inserted into plasmids that can be used to transform the bacteria.
Step-by-step explanation:
Genetic engineering is the process of manipulating an organim's genome in order to yield a desirable result. According to this question, a vaccine is to be created using an antigen that will trigger an immune response against the particular disease in the involved organism.
However, the antigens needs to be produced by genetically engineering/modifying bacteria. To do this, the gene coding for the antigen can be inserted into plasmids, an extra-chromosomal DNA, that can be used to transform the bacteria. In other words, the plasmid + antigen gene, which represents the recombinant DNA will confer upon the transformed bacteria the ability to produce the antigen.