To calculate how many groups of 6 he can pick out of 16 students you have to calculate a combination. To do so you have to apply the following formula:
![C_((r,n))=(n!)/(r!(n-r)!)](https://img.qammunity.org/2023/formulas/mathematics/college/hy0aeisbrt9udosbnvc8gg11zuim4qdluw.png)
Where
n represents the total number of students in the class
r represents the number of students he wants to pick up
So for this exercise you have to use n=16 and r=3
![\begin{gathered} C_{}(3,16)=(16!)/(3!(16-3)!) \\ C(3,16)=560 \end{gathered}](https://img.qammunity.org/2023/formulas/mathematics/college/b4tkwm04k4inkg6l39pj5nrarzdafj01xh.png)
The principal can pick up to 560 different groups of Ms Guzman's class.