By definition, a Perfect square trinomial has the following form:

Perfect square trinomials can be expressed in Squared-binomial form, as following:

In this case, you know that the first term of the Perfect square trinomial Tia wrote on the board, is:

And the last term is:

Then you can identify that:

Solving for "a", you get:
![\begin{gathered} a=\sqrt[]{4x^2} \\ a=2x \end{gathered}](https://img.qammunity.org/2023/formulas/mathematics/college/e9ggmvjwfq54yqddmw6gwh3s3kuzeouf51.png)
Notice that:

Solving for "b", you get:
![\begin{gathered} b=\sqrt[]{25} \\ b=5 \end{gathered}](https://img.qammunity.org/2023/formulas/mathematics/college/pvw1x11kjzj0snh6uc87rjw120ieq0dmsf.png)
Knowing "a" and "b", you can write the following Squared-binomial:

And determine that the missing term is:

Therefore, the missing value is not a Perfect square, because it is not obtained by multiplying two equal Integers.
The answer is: Option B.