Answer:
the concentration of the solute is lower inside the cell than outside it
Step-by-step explanation:
This question depicts the process of ACTIVE TRANSPORT, which is the movement of a substance against concentration gradient, hence, requires energy input (ATP) to occur. In this case, transporting a solute from inside an animal cell to the extracellular fluid across the cell membrane always requires energy.
This is because the concentration of solute inside the cell is much lower than that of the extracellular fluid, hence, to move the solutes against this concentration gradient (low to high), energy in form of ATP is required.