First, we have to find the slope of the given line.
We use the following formula to find the slope.
Let's replace the points (-3, -4) and (5, 0) in the formula.
The slope of the given line is 1/2.
Now, we find the slope of the new perpendicular line with the following formula.
The slope of the given perpendicular line is -2.
Notice that C is the only equation that has a slope of -2 because the coefficient of x is -2.
Therefore, the answer is C.