Prokaryotic and eukaryotic cells have a few differences, and some or them are related to the process of transcription. The first difference is that in prokaryotic cells, the transcription and also the release and processing of the RNA takes place in the cytoplasm, while in eukaryotic it occurs in the nucleous. A second point is that the transcription and translation happen at the same time in prokaryotic cells and in different moments in eukaryotic. Also, in prokaryotic cells the RNA polymerases are composed by 5 polypeptides and the transcription doesn`t require factors for its initiation. In eukaryotic cells, the RNA polymerases are composed by 10 polypeptides or more, and the transcription requires transcription factors in order to initiate.