Solution:
The meme character is in love with someone else. Seeing her, the meme character (Howard), gasps for breath. If he runs out of breath he must find another way to survive to carry out his cellular functions and not die.
Cellular reactions where there is no presence of oxygen are called anaerobic reactions, among them is anaerobic cellular respiration which is a biological process carried out by anaerobic microorganisms, which consists of the oxidation-reduction of monosaccharides and other compounds in which the terminal electron acceptor is an inorganic molecule other than oxygen.
This meme is funny because human beings are aerobic organisms that need oxygen for their metabolic reactions. Therefore, Wolowitz will still die because he is an aerobic organism.