Step-by-step explanation:
Remember that enzymes are proteins that help catalyze reactions. If the pH changes, the basic and acidic R groups of the amino acids in the protein lose their ionic charges, which causes a change in the shape of the protein and disables it. On the other hand, there is also denaturation of the proteins and therefore of the enzymes when the temperature increases, this is due to the fact that at high temperatures the kinetic energy of the molecules increases, which disorganizes the three-dimensional structure of the proteins.
These denaturation processes can be seen in the next diagram:
We can conclude that the correct answer is:
Answer: