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29 votes
Why cant you eat grapefruit with certain medications

User Luis Miguel
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1 Answer

11 votes
11 votes

Answer:

Many drugs are broken down (metabolized) with the help of a vital enzyme called CYP3A4 in the small intestine. Grapefruit juice can block the action of intestinal CYP3A4, so instead of being metabolized, more of the drug enters the blood and stays in the body longer. The result: too much drug in your body.

Step-by-step explanation:

User Tejs
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