There are 6 democrats and 6 republicans.
The possible ways of selecting 2 democrats is given by the combination:

The possible ways of selecting 4 republicans is:

Now, using the fundamental counting principl, the number of ways of selecting 2 democrats and 4 republicans is:

The total number of possible combinations is given by:

Finally the probability is given by:

Therefore:

Hence the probability is 75/308