a)
The drug causes side effects for 18% of patients, that is, every patient who was exposed to the drug has p = 18% chance of have side effects.
If X represent the number of patients who experience side effects betwen n = 230 observed, and considering a binomial distribution, we have:

Since or data set only deals with whole numbers, we can approximate the mean to 41
The variance is given by:

Then, the standard deviation of X is:

b)
The mean is the expected value of a variable. That is, most probable value to be identified,
c)
Since the 95% tolerance range is between 29 and 53, is would be usual if 32 patients experience side effects