Question

Based on the equation below, which of the following would be true when [Ligand] = Kd?a) All of the receptors will be bound by ligand.b) The amount of free ligand will equal the amount of ligand-receptor complex.c) The amount of free ligand will equal the amount of free receptor.d) The amount of free receptor will equal the amount of ligand-receptor complex.

Answer 1

Kd stands for ligand concentration at which receptor is half-saturated with ligand or half of the receptors bound.

If in the case that [ligand] has the same Kd, then I think it means the amount of free ligand is the same amount of the receptors with ligand.

ANSWER:

b) The amount of free ligand will equal the amount of ligand-receptor complex.